bioconductor-cn.mops¶
Summary¶
cn.mops (Copy Number estimation by a Mixture Of PoissonS) is a data processing pipeline for copy number variations and aberrations (CNVs and CNAs) from next generation sequencing (NGS) data. The package supplies functions to convert BAM files into read count matrices or genomic ranges objects, which are the input objects for cn.mops. cn.mops models the depths of coverage across samples at each genomic position. Therefore, it does not suffer from read count biases along chromosomes. Using a Bayesian approach, cn.mops decomposes read variations across samples into integer copy numbers and noise by its mixture components and Poisson distributions, respectively. cn.mops guarantees a low FDR because wrong detections are indicated by high noise and filtered out. cn.mops is very fast and written in C++.
Versions¶
- 1.16.2
License¶
LGPL (>= 2.0)
Meta¶
package:
name: bioconductor-cn.mops
version: 1.16.2
source:
fn: cn.mops_1.16.2.tar.gz
url: http://bioconductor.org/packages/release/bioc/src/contrib/cn.mops_1.16.2.tar.gz
md5: a46119b3cf298fb773ca9f7aa8ef34ac
build:
number: 0
rpaths:
- lib/R/lib/
- lib/
requirements:
build:
- bioconductor-biobase
- bioconductor-biocgenerics
- bioconductor-genomicranges
- bioconductor-iranges
- bioconductor-rsamtools
- 'r >=2.12'
run:
- bioconductor-biobase
- bioconductor-biocgenerics
- bioconductor-genomicranges
- bioconductor-iranges
- bioconductor-rsamtools
- 'r >=2.12'
test:
commands:
- '$R -e "library(''cn.mops'')"'
about:
home: http://bioconductor.org/packages/release/bioc/html/cn.mops.html
license: 'LGPL (>= 2.0)'
summary: 'cn.mops (Copy Number estimation by a Mixture Of PoissonS) is a data processing
pipeline for copy number variations and aberrations (CNVs and CNAs) from next
generation sequencing (NGS) data. The package supplies functions to convert BAM
files into read count matrices or genomic ranges objects, which are the input
objects for cn.mops. cn.mops models the depths of coverage across samples at each
genomic position. Therefore, it does not suffer from read count biases along chromosomes.
Using a Bayesian approach, cn.mops decomposes read variations across samples into
integer copy numbers and noise by its mixture components and Poisson distributions,
respectively. cn.mops guarantees a low FDR because wrong detections are indicated
by high noise and filtered out. cn.mops is very fast and written in C++.'